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Histone deacetylases (HDACs), in particular, have emerged as key regulators of astrocyte-mediated neuroinflammation and neurodegeneration

It is then perfectly fine to give Vitamin B12 along with a meal of one's choice that has minimal fats since fat slows the absorption of water-soluble vitamins

NICE Symptoms to watch for (because numbers arent everything) Contact your clinician if you notice new symptoms that persist for a couple of weeks, such as: Possible under-replacement (hypothyroid): fatigue, low mood, feeling cold, constipation, dry skin, slower heart rate Possible over-replacement (hyperthyroid): palpitations, tremor, anxiety, sweating, heat intolerance, diarrhoea, trouble sleeping These symptoms can overlap with diet changes and early Mounjaro side effects, so blood tests help clarify whats going on

Deficiencies in B vitamins may lead to depression